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Biotinylated Recombinant Human ACE2

OVERVIEW
CATALOG # bs-46001P-Biotin
REFERENCE # ACE_HM401B
PRODUCT NAME
Biotinylated Recombinant Human ACE2
CONJUGATION Biotinylated
SOURCE Biotinylated Recombinant human ACE2 is expressed from mammalian with a His-tag and Avi at the C-terminal.
It contains Gln18- Ser740.
EXPRESSION SYSTEM
HEK293
TAG His-Avi
MOLECULAR WEIGHT The protein has a predicted MW of 86.5kDa. Due to glycosylation, the protein migrates to 95-110kDa based on Bis-Tris PAGE result.
ENDOTOXIN
Less than 1EU per ug by the LAL method.
PURITY: > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

FORMULATION
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
STORAGE The product should be stored at -70℃ or -20℃.
TARGET
ACCESSION

BACKGROUND ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.